This special issue of Annals of Clinical Psychiatry features original research and review articles on autism spectrum disorders (ASD) as a continuation of our August issue. A recent survey reports a higher prevalence of ASD in the United States—1.1% or 1 in 91 children age 3 to 17—than previously estimated.1 The survey also reports that nearly 40% of children who had been diagnosed with ASD did not currently have the condition. These results reinforce the importance of early recognition and effective interventions for children with ASD.